A Study of ATG-031 in Advanced Solid Tumors or B-cell Non-Hodgkin Lymphomas

PHASE1RecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

December 8, 2023

Primary Completion Date

December 31, 2026

Study Completion Date

June 30, 2027

Conditions
Advanced Solid TumorsB-cell Non-Hodgkin Lymphomas
Interventions
DRUG

ATG-031

ATG-031 will be infused Q3W on Day 1 of each cycle, at the starting dose of 0.03 mg/kg and a maximum dose of 9 mg/kg in the Dose Escalation Phase, and the defined MTD if available or OBD in the Dose Expansion Phase. Based on the emerging PK, PDx, safety, and other relevant data, SRC may decide to explore alternative dosing schedules.

Trial Locations (4)

77030

RECRUITING

University of Texas M.D. Anderson Cancer Center, Houston

80045

RECRUITING

Regents of the University of Colorado, Aurora

94102

RECRUITING

University of California San Francisco (UCSF), San Francisco

06520- 8087

RECRUITING

Yale University, New Haven

All Listed Sponsors
lead

Antengene Biologics Limited

INDUSTRY