A Study to Evaluate Drug-Drug Interaction of TQ05105 Tablets

PHASE1UnknownINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

September 30, 2023

Primary Completion Date

October 31, 2023

Study Completion Date

December 31, 2023

Conditions
Myelofibrosis
Interventions
DRUG

TQ05105 tablets

TQ05105 is a Janus kinase 2 (JAK2) inhibitor.

DRUG

Itraconazole capsule

Itraconazole is a strong inhibitor of cytochrome P450 3A (CYP3A).

DRUG

Rifampicin Capsule

Rifampicin is a strong inducer of CYP3A.

Trial Locations (1)

250021

Shandong Provincial Hospital, Jinan

All Listed Sponsors
lead

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

INDUSTRY