36
Participants
Start Date
September 10, 2023
Primary Completion Date
March 31, 2028
Study Completion Date
April 10, 2030
Transcutaneous spinal cord stimulator
Stimulation to the spinal cord will be administered using Neostim/Biostim (Cosyma Inc., Denver CO) device by applying up to five conductive electrodes placed on the skin at the midline over the thoracic levels as cathodes between T1 to T8, and up to four self-adhesive electrodes located symmetrically on the skin over the iliac crests and shoulders as anodes.
Respiratory Training
Standard threshold Positive Expiratory Pressure Device (PEP, Respironics Inc., Cedar Grove, NJ) and standard threshold Inspiratory Muscle Trainer (IMT, Respironics Inc., Cedar Grove, NJ) assembled together using a T-shaped connector with a flanged mouthpiece (Airlife 001504) will be used for the respiratory training intervention.
RECRUITING
Frazier Rehabilitation and Neuroscience Institute, Louisville
National Heart, Lung, and Blood Institute (NHLBI)
NIH
University of Louisville
OTHER