Spinal Cord Stimulation for Respiratory Rehabilitation in Patients With Chronic Spinal Cord Injury

NARecruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

September 10, 2023

Primary Completion Date

March 31, 2028

Study Completion Date

April 10, 2030

Conditions
Spinal Cord InjuriesRespiration Disorders
Interventions
DEVICE

Transcutaneous spinal cord stimulator

Stimulation to the spinal cord will be administered using Neostim/Biostim (Cosyma Inc., Denver CO) device by applying up to five conductive electrodes placed on the skin at the midline over the thoracic levels as cathodes between T1 to T8, and up to four self-adhesive electrodes located symmetrically on the skin over the iliac crests and shoulders as anodes.

DEVICE

Respiratory Training

Standard threshold Positive Expiratory Pressure Device (PEP, Respironics Inc., Cedar Grove, NJ) and standard threshold Inspiratory Muscle Trainer (IMT, Respironics Inc., Cedar Grove, NJ) assembled together using a T-shaped connector with a flanged mouthpiece (Airlife 001504) will be used for the respiratory training intervention.

Trial Locations (1)

40202

RECRUITING

Frazier Rehabilitation and Neuroscience Institute, Louisville

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

University of Louisville

OTHER