A Study to Evaluate the Safety, Tolerability, and Weight Loss Efficacy of K-757 Alone and in Combination With K-833

PHASE2CompletedINTERVENTIONAL
Enrollment

155

Participants

Timeline

Start Date

September 15, 2023

Primary Completion Date

February 7, 2024

Study Completion Date

February 19, 2024

Conditions
Obesity
Interventions
DRUG

K-757 120 mg BID and K-833 100 mg BID

"K-757 was titrated to the maintenance dose of 120 mg twice daily (BID) by Day 22. K-833 was initiated at 100 mg once daily in the morning (QAM) and was titrated to the maintenance dose of 100 mg BID on Day 8.~Both administered orally."

DRUG

K-757 120 mg BID and matching placebo to K-833

"K-757 was titrated to the maintenance dose of 120 mg twice daily (BID) by Day 22.~Both administered orally."

DRUG

Matching placebo to K-757 and matching placebo to K-833

Both administered orally.

Trial Locations (22)

14609

Rochester Clinical Research, Rochester

17011

Capital Area Research, LLC, Camp Hill

19611

Reading Hospital Clinical Trials Office, West Reading

20782

MedStar Health Research Institute, Hyattsville

22206

Washington Center for Weight Management and Research, Inc., Arlington

22911

Charlottesville Medical Research, Charlottesville

23606

Health Research of Hampton Roads, Inc, Newport News

27408

Medication Management, LLC (PharmQuest), Greensboro

28401

Wilmington Health (Accellacare of Wilmington), Wilmington

29303

Spartanburg Medical Research, Spartanburg

30281

Clinical Research Atlanta, Stockbridge

40213

L-MARC Research Center, Louisville

44281

Family Practice Center of Wadsworth, Inc dba New Venture Medical Research, Wadsworth

48334

Quest Research Institute, Farmington Hills

66606

Cotton O'Neil Clinical Research Center, Topeka

73069

AMR Norman, Norman

76180

North Hills Family Medicine/North Hills Medical Research, North Richland Hills

78229

Clinical Trials of Texas, LLC, San Antonio

78526

Headlands Research - Brownsville, Brownsville

92103

Artemis Institute for Clinical Research, LLC, San Diego

97210

Summit Headlands LLC, Portland

01844

ActivMed Practices and Research, LLC, Portsmouth

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Kallyope Inc.

INDUSTRY