Efficacy of Modified Fruquintinib in Colorectal Cancer Liver Metastases: A Phase II Study

PHASE2RecruitingINTERVENTIONAL
Enrollment

64

Participants

Timeline

Start Date

May 1, 2023

Primary Completion Date

August 1, 2024

Study Completion Date

August 1, 2026

Conditions
Colorectal Cancer Metastatic
Interventions
DRUG

Fruquintinib

"Drug:~Maintenance treatment regimen:~Fruquintinib 5 mg, qd, po, with three weeks of continuous treatment followed by one week of drug discontinuation. Each treatment cycle lasts four weeks. The treatment will be continued for six months, or until tumor recurrence, metastasis, or intolerable drug toxicities occur within six months.~Adverse drug reactions that occur during the trial will be graded according to the NCI CTCAE version 5.0 and dose adjustments will be made according to the corresponding rules."

Trial Locations (1)

510062

RECRUITING

Colorectal Department,SunYat-sen University Cancer Center, Guangzhou

All Listed Sponsors
lead

Sun Yat-sen University

OTHER