A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

April 1, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Cystic Fibrosis LungRespiratory Infections, Recurrent, ChronicPseudomonas Aeruginosa
Interventions
DRUG

RSP-1502

RSP-1502 is a sterile, preservative free solution to be administered by inhalation via a nebulizer. Each dose of RSP-1502 contains the active components tobramycin (300 mg) and CaEDTA in a 5 mL solution.

DRUG

Tobramycin inhalation solution

Tobramycin inhalation solution is 300 mg tobramycin in 5 mL solution.

Trial Locations (21)

10027

RECRUITING

Columbia University Cystic Fibrosis Program, New York

19104

RECRUITING

University of Pennsylvania, Philadelphia

30912

RECRUITING

Augusta University, Augusta

43205

RECRUITING

Nationwide Children's Hospital, Columbus

44106

RECRUITING

Rainbow Babies and Children's Hospital / University Hospitals Cleveland Medical Center, Cleveland

55403

RECRUITING

The Minnesota Cystic Fibrosis Center, Minneapolis

63130

RECRUITING

Washington University School of Medicine, St Louis

70118

RECRUITING

Tulane University, New Orleans

78723

RECRUITING

Dell Children's Medical Center of Central Texas, Austin

85750

RECRUITING

Tucson Cystic Fibrosis Center, Tucson

90033

RECRUITING

Center for Cystic Fibrosis at Keck Medical Center of USC, Los Angeles

94305

RECRUITING

Stanford University Medical Center, Palo Alto

Unknown

RECRUITING

Royal Prince Albert Hospital, Camperdown

RECRUITING

Westmead Hospital, Westmead

RECRUITING

Queensland Children's Hospital, Brisbane

RECRUITING

The Prince Charles Hospital, Brisbane

RECRUITING

Royal Adelaide Hospital, Adelaide

RECRUITING

The Alfred Hospital, Melbourne

RECRUITING

The Royal Children's Hospital, Parkville

RECRUITING

Lung Institute of Western Australia, Nedlands

RECRUITING

The Kids Research Institute Australia, Perth Children's Hospital, Perth

All Listed Sponsors
lead

Respirion Pharmaceuticals Pty Ltd

INDUSTRY