172
Participants
Start Date
September 1, 2023
Primary Completion Date
November 4, 2028
Study Completion Date
July 4, 2029
MCLA-129: 1500mg or 2000mg IV Q2W
Every 28 days is a cycle until disease progression, death, initiation of new anti-tumor treatment, loss of follow-up, or voluntary withdrawal occurs
Befotertinib: 75 mg or 100 mg Po QD
"The initial dose of Befotertinib is 75 mg orally once daily (QD) for one cycle, and then increased to 100 mg orally QD in the absence of CTCAE grade ≥ 2 headache or thrombocytopenia during the first cycle, otherwise maintained to 75 mg orally QD.~Every 28 days is a cycle until disease progression, death, initiation of new anti-tumor treatment, loss of follow-up, or voluntary withdrawal occurs."
The first affiliated hospital of bengbu medical college, Bengbu
Hunan cancer hospital, Changsha
Shanghai chest hospital, Shanghai
Lead Sponsor
Betta Pharmaceuticals Co., Ltd.
INDUSTRY