An Exploratory Clinical Study Evaluating the Safety and Efficacy of Anti-CEA-CAR-T Cells Injection in Patients With CEA+ Locally Advanced and/or Metastatic Solid Tumors

PHASE1RecruitingINTERVENTIONAL
Enrollment

9

Participants

Timeline

Start Date

October 23, 2023

Primary Completion Date

September 1, 2026

Study Completion Date

September 1, 2026

Conditions
Carcinoma
Interventions
BIOLOGICAL

Intravenous infusion anti-CEA-CAR-T cell

Anti-CEA-CAR-T cell is administered as a single intravenous infusion. Follow-up infusions are based on the investigator's decision.The dose group to be infusion was 0.3×10\^7 CAR-T cells/kg, 1×10\^7 CAR-T cells/kg, and 3×10\^7 CAR-T cells/kg based on the 3+3 dose escalation principle. The infusion dose refers to the number of CAR-positive cells.

Trial Locations (1)

110001

RECRUITING

The First Affiliated Hospital of China Medical Univeristy, Shenyang

All Listed Sponsors
collaborator

Shanghai First Song Therapeutics Co., Ltd

INDUSTRY

lead

China Medical University, China

OTHER