Azithromycin as Adjunctive Treatment for Uncomplicated Severe Acute Malnutrition

PHASE4RecruitingINTERVENTIONAL
Enrollment

3,000

Participants

Timeline

Start Date

October 23, 2024

Primary Completion Date

June 30, 2028

Study Completion Date

December 29, 2028

Conditions
Malnutrition, ChildSevere Acute Malnutrition
Interventions
DRUG

Azithromycin

oral azithromycin (20 mg/kg, single directly observed dose, oral suspension),

DRUG

Amoxicillin

Standard of Care. A 7-day, twice-daily course of amoxicillin will be offered as a syrup to children (80 mg/kg divided into twice-daily doses, estimated with weight-based dosing).

OTHER

Placebo

A 7-day, twice-daily course of placebo will be offered as a syrup to children (80 mg/kg divided into twice-daily doses, estimated with weight-based dosing).

Trial Locations (1)

Unknown

RECRUITING

Centre de recherche en Santé de nouna, Nouna

All Listed Sponsors
collaborator

Centre de Recherche en Sante de Nouna, Burkina Faso

OTHER_GOV

collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

lead

University of California, San Francisco

OTHER