Neoadjuvant Tislelizumab Plus Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer (NeoSPOT)

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

110

Participants

Timeline

Start Date

June 27, 2023

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2027

Conditions
Oral Squamous Cell CarcinomaOropharyngeal Squamous Cell Carcinoma
Interventions
DRUG

Tislelizumab

Dose: 200 mg Route: Intravenous infusion Frequency \& treatment mode: Day 1, every 3 weeks

DRUG

Albumin-Bound Paclitaxel

Dose: 260 mg/m\^2 Route: Intravenous infusion Frequency \& treatment mode: Day 1, every 3 weeks

DRUG

Cisplatin

Dose: 60-75 mg/m\^2 Route: Intravenous infusion Frequency \& treatment mode: Day 1, every 3 weeks

Trial Locations (13)

100000

Peking University School and Hospital Stomatology, Beijing

Unknown

Affiliated Hospital of Hebei University, Baoding

Tangshan People's Hospital, Tangshan

The First Affiliated Hospital of Harbin Medical University, Harbin

Affiliated Hospital of Chifeng College, Chifeng

The Affiliated Hospital of Inner Mongolia Medical University, Hohhot

The Hospital of Stomatology of Jilin University, Changchun

China Medical University School and Hospital Of Stomatology, Shenyang

Shandong Provincial Hospital, Jinan

The Affiliated Hospital of Qingdao University, Qingdao

First Hospital of Shanxi Medical University, Taiyuan

Shanxi Cancer hospital, Taiyuan

Tianjin First Central Hospital, Tianjin

All Listed Sponsors
lead

Peking University Hospital of Stomatology

OTHER