Retraining and Control Therapy (ReACT) R33 Phase

NARecruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

March 9, 2024

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2026

Conditions
Convulsion, Non-Epileptic
Interventions
BEHAVIORAL

ReACT

ReACT is a novel cognitive behavioral treatment and is a PNES intervention that targets sense of control and catastrophic symptom expectations. ReACT consists of 12 sessions of therapy focused on teaching adolescents to regain control of their body through managing thoughts and behaviors that reinforce the PNES and return to previous activities. It teaches parents how to respond to PNES in a manner that encourages the adolescents to regain control of their body. The PNES is explained as behaviors learned through classical and operant conditioning.

BEHAVIORAL

Supportive Therapy

The supportive therapy treatment consists of 12 sessions of therapy focused on discussing daily difficulties and/or stressors they experience and identifying stress triggers for PNES. The PNES is explained as physical manifestations of psychological stress.

Trial Locations (1)

35294

RECRUITING

University of Alabama at Birmingham, Birmingham

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

University of Alabama at Birmingham

OTHER