A Study to Understand the Effects of Carbamazepine on How Vepdegestrant is Processed in Healthy Participants

PHASE1CompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

August 18, 2023

Primary Completion Date

October 11, 2023

Study Completion Date

November 21, 2023

Conditions
Healthy Participants
Interventions
DRUG

Vepdegestrant

Participants will receive a single dose of Vepdegestrant by mouth in Period 1 and Period 2, with a washout period of at least 20 days between two doses of Vepdegestrant.

DRUG

Carbamazepine

Participants will receive Carbamazepine by mouth once a day for 19 days in Period 2.

Trial Locations (1)

B-1070

Pfizer Clinical Research Unit - Brussels, Brussels

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Arvinas Estrogen Receptor, Inc.

INDUSTRY

lead

Pfizer

INDUSTRY

NCT06005688 - A Study to Understand the Effects of Carbamazepine on How Vepdegestrant is Processed in Healthy Participants | Biotech Hunter | Biotech Hunter