Estradiol Therapy In Transgender Women to Research Interactions With HIV Therapy

PHASE2CompletedINTERVENTIONAL
Enrollment

93

Participants

Timeline

Start Date

January 4, 2024

Primary Completion Date

August 21, 2025

Study Completion Date

August 21, 2025

Conditions
HIV I Infection
Interventions
DRUG

Estradiol

Oral 17-β estradiol 2 mg once daily will be initiated at study entry. At weeks 4, 12, 24, and 36, study clinicians may titrate 17-β estradiol in 2 mg increments to achieve the desired participant goals and target hormone concentrations, as measured locally at each visit.

Trial Locations (18)

4

Barranco CRS (11301), Lima

10065

Weill Cornell Uptown CRS (site 7803), New York

10330

Thai Red Cross AIDS Research Centre (TRC-ARC) CRS (31802), Bangkok

14080

Nutrición-Mexico CRS (32078), Mexico City

20005

Whitman-Walker Institute, Inc. CRS (31791), Washington D.C.

21205

Johns Hopkins University CRS (201), Baltimore

27401

Greensboro CRS (3203), Greensboro

30308

The Ponce de Leon Center CRS (5802), Atlanta

37204

Vanderbilt Therapeutics CRS, Nashville

44106

Case CRS (2501), Cleveland

50200

Chiang Mai University HIV Treatment (CMU HIV Treatment) CRS (31784), Chiang Mai

77030

Houston AIDS Research Team CRS (31473), Houston

80045

University of Colorado Hospital CRS (6101), Aurora

92103

UCSD Antiviral Research Center CRS (701), San Diego

94110

University of California, San Francisco HIV/AIDS CRS (801), San Francisco

63110-1010

Washington University Therapeutics (WT) CRS (2101), St Louis

07103

New Jersey Medical School Clinical Research Center CRS (31786), Newark

27599-7215

Chapel Hill CRS (3201), Chapel Hill

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT06005610 - Estradiol Therapy In Transgender Women to Research Interactions With HIV Therapy | Biotech Hunter | Biotech Hunter