Study to Evaluate SBRT for EGFR Mutant NSCLC Patients Receiving Osimertinib (CULTRO)

NANot yet recruitingINTERVENTIONAL
Enrollment

35

Participants

Timeline

Start Date

November 30, 2023

Primary Completion Date

November 30, 2026

Study Completion Date

November 30, 2028

Conditions
EGF-R Positive Non-Small Cell Lung CancerNon Small Cell Lung CancerEGFR Exon 19 DeletionEGFR Exon 21 MutationEGFR G719X
Interventions
RADIATION

Stereotactic Body Radiation Therapy SBRT

This is a non-randomized Phase II study in which all patients receive the experimental treatment with Stereotactic Ablative Radiotherapy (SABR) to residual tumor lesions (up to 5 residual metastatic lesions in a maximum of 2 organs) following 12 weeks of systemic treatment with Osimertinib. The study aims to enroll 35 patients diagnosed and treated at CTIC Centro de Tratamiento e Investigación Sobre Cáncer Luis Carlos Sarmiento Angulo.

Trial Locations (1)

Unknown

CTIC - Centro de Tratamiento e Investigación Sobre Cáncer Luis Carlos Sarmiento Angulo, Bogotá

All Listed Sponsors
lead

Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo

OTHER

NCT05998993 - Study to Evaluate SBRT for EGFR Mutant NSCLC Patients Receiving Osimertinib (CULTRO) | Biotech Hunter | Biotech Hunter