Anthrax AV7909 Boost Evaluation Study

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

220

Participants

Timeline

Start Date

December 5, 2023

Primary Completion Date

August 28, 2025

Study Completion Date

August 31, 2026

Conditions
Anthrax
Interventions
BIOLOGICAL

AV7909 Full Dose (0.5 mL)

AV7909 Anthrax Vaccine is being developed by Emergent Product Development Gaithersburg Inc. (Emergent) for PEP of disease in persons 18 through 65 years of age following suspected or confirmed B. anthracis exposure when administered in conjunction with the recommended antibacterial regimen. AV7909 is a combination product containing BioThrax and CPG 7909, a synthetic immunostimulatory oligodeoxynucleotide that has been shown to be a potent vaccine adjuvant. CPG 7909 is a Toll-like receptor 9 agonist designed to induce both an enhanced antigen-specific antibody response and a natural killer T-cell immune response when used in combination with prophylactic (preventative) or therapeutic vaccines.

BIOLOGICAL

AV7909 Half Dose (0.25 mL)

AV7909 Anthrax Vaccine is being developed by Emergent Product Development Gaithersburg Inc. (Emergent) for PEP of disease in persons 18 through 65 years of age following suspected or confirmed B. anthracis exposure when administered in conjunction with the recommended antibacterial regimen. AV7909 is a combination product containing BioThrax and CPG 7909, a synthetic immunostimulatory oligodeoxynucleotide that has been shown to be a potent vaccine adjuvant. CPG 7909 is a Toll-like receptor 9 agonist designed to induce both an enhanced antigen-specific antibody response and a natural killer T-cell immune response when used in combination with prophylactic (preventative) or therapeutic vaccines.

Trial Locations (7)

27103

Accellacare of Winston-Salem, Winston-Salem

28144

Accellacare of Salisbury, Salisbury

28601

Accellacare of Hickory, Hickory

28625

Accellacare of Piedmont, Statesville

37760

Accellacare Knoxville, Jefferson City

37912

Accellacare Knoxville, Knoxville

37938

Accellacare Knoxville, Knoxville

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Rho Federal Systems Division, Inc.

INDUSTRY

collaborator

ICON plc

INDUSTRY

lead

Biomedical Advanced Research and Development Authority

FED

NCT05997264 - Anthrax AV7909 Boost Evaluation Study | Biotech Hunter | Biotech Hunter