Study for Evaluation of Safety and Efficacy of PADN to Treat Combined Post- and Pre- Capillary Pulmonary Hypertension Associated with Chronic Heart Failure(PADN-CpcPH-PILOT)

NARecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

June 28, 2024

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Pulmonary HypertensionHeart Failure
Interventions
PROCEDURE

Pulmonary Artery Denervation

"Contrast pulmonary artery (PA) angiography will be performed to localize the pulmonary artery bifurcation level and calculate the PA diameter. Once the anatomy deemed acceptable, the radiofrequency ablation catheter will be introduced into ostium of the left PA and the distal bifurcation area of the main PA.~The catheter will be manoeuvred within the PA to allow energy delivery in a circumferential manner to ensure that the electrodes are tightly in contact with the endovascular surface. About three ablations at 45-55°C for 120 seconds each will be performed in ostium of the left PA and the distal bifurcation area of the main PA."

Trial Locations (1)

Unknown

RECRUITING

Hospital de Santa Marta, Lisbon

All Listed Sponsors
lead

Pulnovo Medical (Wuxi) Co., Ltd.

INDUSTRY