NCT05992610 - Induction Treatment in SCC of the Head and Neck Region - Concomitant Chemotherapy and Low-dose Radiotherapy | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

February 17, 2022

Primary Completion Date

March 31, 2025

Study Completion Date

March 31, 2026

Conditions

Squamous Cell Carcinoma of Oral CavityPharynx CarcinomaLarynx CarcinomaParanasal Sinus Carcinoma

Interventions

OTHER

Chemotherapy (carboplatin+paclitaxel) with concomitant low dose ionizing radiotherapy

"Chemotherapy based on carboplatin 6 AUC + paclitaxel 75 mg/m2.~Radiotherapy:~D:1 - 2 x 0,5 Gy (first dose up to one hour after the end of the carboplatin infusion, second dose 3 to 6 hours later), D:2 - 2 x 0,5 Gy (interval between doses not less than 3 hours), D:8 and D:15 - 2 x 0,5 Gy (first dose up to one hour after the end of the chemotherapeutic infusion, second dose 3 to 6 hours later)."

Trial Locations (1)

44-102

RECRUITING

The Maria Sklodowska-Curie National Research Institute of Oncology, Branch in Gliwice, Gliwice