A Study to Evaluate the Safety and Immunogenicity of ChAdOx1-VZV in Healthy Adults Aged 50-65 Years

PHASE1CompletedINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

November 7, 2023

Primary Completion Date

November 4, 2024

Study Completion Date

November 4, 2024

Conditions
Herpes Zoster
Interventions
BIOLOGICAL

Recombinant Zoster Vaccine (Adenovirus Vector) (ChAdOx1-VZV)

2 doses of ChAdOX1-VZV vaccine on Day 0 and Month 4

BIOLOGICAL

Zoster Vaccine Recombinant, Adjuvanted (Shingrix)

2 doses of Shingrix vaccine on Day 0 and Month 4

BIOLOGICAL

ChAdOx1-VZV

2 doses of ChAdOX1-VZV vaccine on Day 0 and Month 4

BIOLOGICAL

Shingrix

2 doses of Shingrix vaccine on Day 0 and Month 4

BIOLOGICAL

IH ChAdOx1-VZV

2 doses of ChAdOX1-VZV vaccine on Day 0 and Month 4

BIOLOGICAL

IH saline

2 doses of saline on Day 0 and Month 4

Trial Locations (1)

Unknown

Canadian Center for Vaccinology, Halifax

Sponsors
All Listed Sponsors
lead

CanSino Biologics Inc.

INDUSTRY

NCT05991427 - A Study to Evaluate the Safety and Immunogenicity of ChAdOx1-VZV in Healthy Adults Aged 50-65 Years | Biotech Hunter | Biotech Hunter