2,100
Participants
Start Date
January 26, 2024
Primary Completion Date
September 1, 2026
Study Completion Date
September 1, 2026
Oral swab molecular testing
Swab-based testing provides a non-invasive approach to collect respiratory specimens for TB testing. Data in adults suggests that swab-based testing could be valuable when sputum collection is not feasible or available.
Automated Cough Sound Analysis
Cough sounds can be collected through a mobile phone and tablet, and then analyzed with machine learning algorithms to predict TB.
Automated Lung Sound Analysis
Lung sounds can be collected with a non-invasive digital stethoscope, and then saved on a tablet or phone and analyzed by machine learning algorithms to predict TB.
Chest X Ray Computer Aided Detection
Several artificial intelligence algorithms have been developed to predict TB, though this has not yet been validated in children.
RECRUITING
Instituto Nacional de Saúde, Maputo
NOT_YET_RECRUITING
Dora Nginza Hospital, Cape Town
NOT_YET_RECRUITING
Mulago National Referral Hospital, Kampala
Instituto Nacional de Saúde, Mozambique
OTHER_GOV
National Referral Hospital
OTHER_GOV
University of Cape Town
OTHER
Johns Hopkins University
OTHER
Elizabeth Glaser Pediatric AIDS Foundation
OTHER
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
University of California, Irvine
OTHER
University of California, San Francisco
OTHER