120
Participants
Start Date
October 19, 2023
Primary Completion Date
October 31, 2026
Study Completion Date
October 31, 2026
Buccal Buprenorphine 300 mcg
buprenorphine for 300mcg buccal administration
Buccal Buprenorphine 600 mcg
buprenorphine for 600mcg buccal administration
Buccal Buprenorphine 900 mcg
buprenorphine for 900mcg buccal administration. Note: This arm has been discontinued as of 06/25/2024 and has been replaced with the 450mcg buprenorphine buccal administration arm.
Buccal Placebo
Placebo for buccal administration
Oral Placebo
Placebo for oral administration
Oral immediate-release oxycodone 10mg
Immediate-release oxycodone for 10 mg oral administration
Buccal Buprenorphine 450mcg
buprenorphine for 450mcg buccal administration. Note: This arm has been added to replace the 900mcg buprenorphine buccal administration arm.
RECRUITING
Vanderbilt University Medical Center, Nashville
National Institute on Drug Abuse (NIDA)
NIH
Vanderbilt University Medical Center
OTHER