PD-1 Inhibitor Therapy Versus Radiotherapy in pCR Patients With Locally Advanced HNSCC After Neoadjuvant Immunochemotherapy

PHASE3RecruitingINTERVENTIONAL
Enrollment

324

Participants

Timeline

Start Date

January 1, 2023

Primary Completion Date

December 31, 2030

Study Completion Date

December 31, 2030

Conditions
HNSCCRadiotherapyPD-1
Interventions
DRUG

PD-1inhibitor

The PD-1 monoclonal antibody was the same as the neoadjuvant therapy before surgery, and the postoperative level was maintained at Q3\*6.

RADIATION

concurrent chemoradiotherapy

According to the guidelines, concurrent chemoradiotherapy is required, and carboplatin (50mg/m2) plus concurrent radiotherapy or cisplatin (30mg/m2) plus concurrent radiotherapy is optional.

Trial Locations (1)

510000

RECRUITING

Sun yat-sen memorial hospital, Guangzhou

All Listed Sponsors
collaborator

First People's Hospital of Foshan

OTHER

collaborator

First Affiliated Hospital, Sun Yat-Sen University

OTHER

collaborator

Affiliated Cancer Hospital & Institute of Guangzhou Medical University

OTHER

collaborator

Affiliated Cancer Hospital of Shantou University Medical College

OTHER

lead

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER