BettER: Biomarker Driven Early Therapeutic Selection in Patients With HR+ HER2- Metastatic or Unresectable Breast Cancer

NARecruitingINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

September 25, 2024

Primary Completion Date

September 30, 2034

Study Completion Date

September 30, 2034

Conditions
Metastatic Breast CancerUnresectable Breast Cancer
Interventions
DEVICE

DiviTum® TKa assay

Will be utilized for determination of serum enzymatic activity of TK1 according to the manufacturer's instructions

DRUG

CDK4/6 + Endocrine therapy

FDA-approved endocrine therapy plus CDK4/6 inhibitor. Ribociclib is the preferred CDK4/6 inhibitor. In the event this drug cannot be obtained due to insurance authorization or if there are specific side effect profile concerns from the treating physician, an alternative CDK4/6 inhibitor is allowed.

Trial Locations (1)

63110

RECRUITING

Washington University School of Medicine, St Louis

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Biovica

UNKNOWN

lead

Washington University School of Medicine

OTHER