43
Participants
Start Date
July 10, 2023
Primary Completion Date
December 31, 2024
Study Completion Date
December 31, 2025
Cyclophosphamide added to standard immunosuppressive therapy with herombopag
Severe aplastic anemia patients will receive a daily dose of Anti-lymphocyte globulin (25mg/kg) for the initial five days at the beginning of the treatment. Cyclosporine will be administered daily at a dosage of 3-5mg/kg. Herombopag will be administered daily at a dosage of 15mg starting from the first day of treatment and continuing for a duration of six months. The moderate-dose cyclophosphamide (20mg/kg) will be administered on days 29-30 and days 43-44.
Regenerative Medicine Center, Tianjin
Institute of Hematology & Blood Diseases Hospital, China
OTHER