Effect of Sodium-glucose Cotransporter-2 Inhibitor in Cellular Senescence in Patients With Cardiovascular Diseases or Type 2 Diabetes

PHASE4RecruitingINTERVENTIONAL
Enrollment

92

Participants

Timeline

Start Date

June 1, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Diabetes MellitusCellular SenescenceSodium-Glucose Transporter 2 Inhibitors
Interventions
DRUG

SGLT2 inhibitor

"For the SGLT2 inhibitor group, total drug adminstration days are 180 days, but non-SGLT2 inhibitor administration period is 3 months, and then changed to the SGLT2 inhibitor another 3 months.~For the SGLT2 inhibitor group, empagliflozin 10mg or dapagliflozin 10mg once daily is administered."

DRUG

Glimepiride

For non-SGLT2 inhibitor (glimepiride) administration period is 3 months, and then changed to the SGLT2 inhibitor another 3 months.

Trial Locations (1)

Unknown

RECRUITING

Yonsei University College of Medicine, Seoul

All Listed Sponsors
lead

Yonsei University

OTHER