pBFS-guided cTBS at Different Doses for Aphasia After Stroke

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

September 22, 2023

Primary Completion Date

September 22, 2025

Study Completion Date

December 22, 2025

Conditions
StrokeAphasia
Interventions
DEVICE

active 1200-pulse continuous Theta Burst Stimulation

Each patient will receive two 600-pulse cTBS stimulations per day, parted by a 15-minute rest period (a total of 1200 pulses daily), for 3-week treatment, with 5 consecutive workdays each week.

DEVICE

active 2400-pulse continuous Theta Burst Stimulation

Each patient will receive two 1200-pulse cTBS stimulations per day, parted by a 30-minute rest period (a total of 2400 pulses daily), for 3-week treatment, with 5 consecutive workdays each week.

DEVICE

active 3600-pulse continuous Theta Burst Stimulation

Each patient will receive two 1800-pulse cTBS stimulations per day, parted by a 50-minute rest period (a total of 3600 pulses daily), for 3-week treatment, with 5 consecutive workdays each week.

DEVICE

sham 1200-pulse continuous Theta Burst Stimulation

Each patient will receive two sham 600-pulse cTBS stimulations per day, parted by a 15-minute rest period (a total of 1200 pulses daily), for 3-week treatment, with 5 consecutive workdays each week.

DEVICE

sham 2400-pulse continuous Theta Burst Stimulation

Each patient will receive two sham 1200-pulse cTBS stimulations per day, parted by a 30-minute rest period (a total of 2400 pulses daily), for 3-week treatment, with 5 consecutive workdays each week.

DEVICE

sham 3600-pulse continuous Theta Burst Stimulation

Each patient will receive two sham 1800-pulse cTBS stimulations per day, parted by a 50-minute rest period (a total of 3600 pulses daily), for 3-week treatment, with 5 consecutive workdays each week.

Trial Locations (2)

Unknown

RECRUITING

Nanshi Hospital of Nanyang, Nanyang

RECRUITING

The fifth Affiliated Hospital of Zhengzhou University, Zhengzhou

Sponsors
All Listed Sponsors
lead

Changping Laboratory

OTHER

NCT05969548 - pBFS-guided cTBS at Different Doses for Aphasia After Stroke | Biotech Hunter | Biotech Hunter