60
Participants
Start Date
September 22, 2023
Primary Completion Date
September 22, 2025
Study Completion Date
December 22, 2025
active 1200-pulse continuous Theta Burst Stimulation
Each patient will receive two 600-pulse cTBS stimulations per day, parted by a 15-minute rest period (a total of 1200 pulses daily), for 3-week treatment, with 5 consecutive workdays each week.
active 2400-pulse continuous Theta Burst Stimulation
Each patient will receive two 1200-pulse cTBS stimulations per day, parted by a 30-minute rest period (a total of 2400 pulses daily), for 3-week treatment, with 5 consecutive workdays each week.
active 3600-pulse continuous Theta Burst Stimulation
Each patient will receive two 1800-pulse cTBS stimulations per day, parted by a 50-minute rest period (a total of 3600 pulses daily), for 3-week treatment, with 5 consecutive workdays each week.
sham 1200-pulse continuous Theta Burst Stimulation
Each patient will receive two sham 600-pulse cTBS stimulations per day, parted by a 15-minute rest period (a total of 1200 pulses daily), for 3-week treatment, with 5 consecutive workdays each week.
sham 2400-pulse continuous Theta Burst Stimulation
Each patient will receive two sham 1200-pulse cTBS stimulations per day, parted by a 30-minute rest period (a total of 2400 pulses daily), for 3-week treatment, with 5 consecutive workdays each week.
sham 3600-pulse continuous Theta Burst Stimulation
Each patient will receive two sham 1800-pulse cTBS stimulations per day, parted by a 50-minute rest period (a total of 3600 pulses daily), for 3-week treatment, with 5 consecutive workdays each week.
RECRUITING
Nanshi Hospital of Nanyang, Nanyang
RECRUITING
The fifth Affiliated Hospital of Zhengzhou University, Zhengzhou
Lead Sponsor
Changping Laboratory
OTHER