NCT05965726View on ClinicalTrials.gov

RECOVER-VITAL: Platform Protocol, Appendix to Measure the Effects of Paxlovid on Long COVID Symptoms

PHASE2CompletedINTERVENTIONAL
Enrollment

964

Participants

Timeline

Start Date

July 26, 2023

Primary Completion Date

December 5, 2024

Study Completion Date

March 13, 2025

Conditions
Long COVID-19Long COVID
Interventions
DRUG

Paxlovid 25 day dosing

nirmatrelvir 300mg and ritonavir 100mg taken bid for 30 days

DRUG

Paxlovid 15 day dosing

nirmatrelvir 300mg and ritonavir 100mg taken bid for 15 days then ritonavir 100mg taken bid plus nirmatrelvir matching placebo bid for 15 days

DRUG

Control

ritonavir 100mg taken bid plus nirmatrelvir matching placebo bid for 30 days

Trial Locations (1)

27710

All sites listed under NCT05595369, Durham

All Listed Sponsors
lead

Kanecia Obie Zimmerman

OTHER