Developing ctDNA Guided Adjuvant Therapy for Gastrooesophageal Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

April 10, 2024

Primary Completion Date

March 31, 2026

Study Completion Date

April 30, 2028

Conditions
Gastrooesophageal Cancer
Interventions
DRUG

Trastuzumab deruxtecan

Trastuzumab deruxtecan is an antibody-drug conjugate that contains trastuzumab covalently linked to deruxtecan, a topoisomerase I inhibitor. It is given by intravenous infusion.

Trial Locations (14)

GU2 7XX

NOT_YET_RECRUITING

Royal Surrey NHS Foundation Trust, Royal Surrey County Hospital, Guildford

CV2 2DX

RECRUITING

University Hospitals Coventry and Warwickshire, University Hospital Coventry, Coventry

BT9 7AB

RECRUITING

Belfast Health and Social Care Trust, Belfast City Hospital, Belfast

CB2 0QQ

RECRUITING

Cambridge University Hospital NHS Foundation Trust, Addenbrookes Hospital, Cambridge

DE22 3NE

RECRUITING

University Hospitals of Derby and Burton NHS Foundation Trust, Royal Derby Hospital, Derby

DD2 1UB

RECRUITING

NHS Tayside, Ninewells Hospital, Dundee

HU16 5JQ

RECRUITING

Hull University Teaching Hospitals NHS Trust, Castel Hill Hospital, Hull

LS9 7TF

RECRUITING

Leeds Teaching Hospitals NHS Trust, St James's University Hospital, Leeds

NW1 2BU

RECRUITING

University College London Hospitals NHS Foundation Trust, University College Hospital London, London

SE1 9RT

RECRUITING

Guys & St Thomas NHS Foundation Trust, Guy's Hospital, London

M20 4BX

RECRUITING

The Christie NHS Foundation Trust, Manchester

OX3 7LE

RECRUITING

Oxford University Hospitals NHS Trust, Churchill Hospital, Oxford

PR2 9HT

RECRUITING

Lancashire Teaching Hospitals NHS Foundation Trust, Royal Preston Hospital, Preston

CF14 2TL

NOT_YET_RECRUITING

Velindre University NHS Trust, Velindre Cancer Centre, Whitchurch

Sponsors

Collaborators (2)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

collaborator

Natera, Inc.

INDUSTRY

lead

University of Southampton

OTHER