Sodium Chloride vs. Glucose Solute as a Volume Replacement Therapy During Decongestion in Acute Heart Failure

PHASE3CompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

February 1, 2022

Primary Completion Date

April 1, 2024

Study Completion Date

April 29, 2024

Conditions
Acute Heart FailureCongestionHeart Failure
Interventions
DRUG

Furosemide intravenous infusion

"At baseline, patients will receive a standardised dose of furosemide 1mg/kg (half of the dose administered as bolus and half as in 2h infusion).~At the 6th and the 12th hour of the study patients will be reassessed and the need for additional diuretics."

DRUG

Continous intravenous infusion of 0.9% Sodium Chloride solution

Continuous 48h infusion of 0.9% sodium chloride at a fixed rate v= 83 ml/h x 24h = 2l/24h

DRUG

Continous intravenous infusion of 5% Glucose solution

Continuous 48h infusion of 5% Glucose at a fixed rate v= 83 ml/h x 24h = 2l/24h

Trial Locations (1)

50-556

Institute of Heart Diseases, Wroclaw Medical University, Wroclaw

All Listed Sponsors
lead

Wroclaw Medical University

OTHER