RC48 Combined With Tislelizumab for Bladder Sparing Treatment in NMIBC With BCG Treatment Failure and HER2 Expression

PHASE2RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

August 5, 2023

Primary Completion Date

June 8, 2026

Study Completion Date

June 8, 2026

Conditions
Non-Muscle Invasive Bladder CancerHER2
Interventions
DRUG

RC48

"RC48 was scheduled to be administered at a dose of 2.0mg/kg every 2 weeks, with the first dose on day 1 of the first cycle.~The drug is diluted with normal saline and administered by intravenous drip for one hour."

DRUG

Tislelizumab

"Tislelizumab was administered at a dose of 200 mg every 3 weeks, with the first dose on day 1 of the first 21-day cycle.~The drug is diluted with normal saline and administered by intravenous drip for one hour."

Trial Locations (1)

Unknown

RECRUITING

Ethics Committee of Shanghai Renji Hospital, Shanghai

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

RemeGen Co., Ltd.

INDUSTRY

collaborator

BeiGene

INDUSTRY

lead

RenJi Hospital

OTHER

NCT05957757 - RC48 Combined With Tislelizumab for Bladder Sparing Treatment in NMIBC With BCG Treatment Failure and HER2 Expression | Biotech Hunter | Biotech Hunter