pBFS Guided 20min Inter-session Interval rTMS Treatment for MDD

NAUnknownINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

July 30, 2023

Primary Completion Date

July 30, 2024

Study Completion Date

August 30, 2024

Conditions
Moderate DepressionMajor Depressive DisorderSevere Depression
Interventions
DEVICE

active rTMS: 20min inter-session interval

Participants will receive active TMS, with 3 sessions per day, 1800 pulses/session, and 20 min inter-session intervals, lasting for 21 days. Individualized targets will be generated using the pBFS method.

DEVICE

active rTMS: 50min inter-session interval

Participants will receive active TMS, with 3 sessions per day, 1800 pulses/session, and 50 min inter-session intervals, lasting for 21 days. Individualized targets will be generated using the pBFS method.

DEVICE

sham rTMS: 20min inter-session interval

The parameters in this group are the same as in the active rTMS: 20min inter-session interval group. Stimulation was delivered by the same device as the active group fitted with a sham coil.

DEVICE

sham rTMS: 50min inter-session interval

The parameters in this group are the same as in the active rTMS: 50min inter-session interval group. Stimulation was delivered by the same device as the active group fitted with a sham coil.

Sponsors
All Listed Sponsors
lead

Changping Laboratory

OTHER

NCT05957341 - pBFS Guided 20min Inter-session Interval rTMS Treatment for MDD | Biotech Hunter | Biotech Hunter