NCT05957016View on ClinicalTrials.gov

Neoadjuvant CIETAI With Concurrent Chemoradiotherapy in Local Advanced Rectal Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

August 30, 2023

Primary Completion Date

June 30, 2025

Study Completion Date

June 30, 2026

Conditions
Rectal Cancer
Interventions
PROCEDURE

CIETAI-R

"1. phase I: (1) Chemo-Immulo-embolization via Tumor Arterial, CIETAI: DSA guided tumor artery infusion of oxaliplatin 130 mg/m2+PD-1 inhibitor (Tirelizumab) 200mg, followed by gelatin sponge particles (350-560um) embolization~2. phase II: Chemoradiotherapy: IMRT：45Gy/25f/5w+capecitabine 1000，po. Bid d1-14, q3w Tirelizumab)200mg ivggt, d1, q3w"

Trial Locations (1)

400042

RECRUITING

Daping Hospital, Third Military Medical University, Chongqing

All Listed Sponsors
lead

Third Military Medical University

OTHER