Multimodal Prehabilitation for Lung Cancer Surgery

NARecruitingINTERVENTIONAL
Enrollment

168

Participants

Timeline

Start Date

June 26, 2023

Primary Completion Date

September 20, 2025

Study Completion Date

March 20, 2026

Conditions
Lung CancerSurgery
Interventions
DIETARY_SUPPLEMENT

Mixed-nutriend supplement (NUT)

Participants will follow ERAS protocol and will receive dietary counselling and anxiety management counselling as needed. They will receive the active multi-nutrient supplement made of whey protein + leucine + vitamin D doses pre-mixed in unlabeled packets prepared by Gruppo Nutrition to dilute in a cup (250 mL) of water. In addition, participants will ingest 15 mL of fruit-flavored fish oil, provided as a liquid oil. They will receive a dosing cup, pre-marked to 15 mL, for a total dose providing 2120 mg eicosapentaenoic acid (EPA) and 1320 mg docosahexaenoic acid (DHA).

OTHER

Multimodal Prehabilitation (MM)

Participants will follow ERAS protocol and will receive dietary counselling and anxiety management counselling as needed. They will receive the NUT intervention + structured exercise training prescribed by a kinesiologist (1. 30 min of aerobic exercise per day of their preferred type (ex. walking) and 2. 30 min of resistance exercise targeting major muscle groups, every second day for 2 sets of 8-12 reps). Training will be performed for 4 weeks prior to surgery (1x/week supervised by kinesiologist at hospital, 2x/week at alone at home)

DIETARY_SUPPLEMENT

Placebo Control (CTRL)

Participants will follow ERAS protocol and will receive dietary counselling and anxiety management counselling as needed. They will receive a placebo dietary supplement made of maltodextrin and sunflower oil.

Trial Locations (1)

H4A 3J1

RECRUITING

Research Institute of the McGill University Health Centre, Montreal

All Listed Sponsors
collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

lead

Stéphanie Chevalier

OTHER