Intra-arterial Albumin Infusion After Endovascular Therapy for Stroke Patients

PHASE1CompletedINTERVENTIONAL
Enrollment

57

Participants

Timeline

Start Date

August 1, 2023

Primary Completion Date

June 29, 2024

Study Completion Date

October 1, 2024

Conditions
Stroke, Acute IschemicAlbuminEndovascular ProceduresLarge Vessel Occlusion
Interventions
BIOLOGICAL

Albumin

In the first phase of the study, a 3 + 3 dose-escalation study with 7 doses (0.25g/kg, 0.35g/kg, 0.40g/kg, 0.45g/kg, 0.5g/kg, 0.55g/kg, 0.60g/kg). Intra-arterial albumin infusion will be applied after successful recanalization of the culprit artery in the anterior circulation. In the second phase of the study, at the maximum safe dose determined in the first phase, an additional 15 to 20 patients will be enrolled for intra-arterial albumin infusion.

Trial Locations (1)

300222

Tianjin Huanhu Hospital, Tianjin

All Listed Sponsors
lead

Tianjin Huanhu Hospital

OTHER