FT522 With Rituximab in Relapsed/Refractory B-Cell Lymphoma (FT522-101)

PHASE1CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

November 16, 2023

Primary Completion Date

June 6, 2025

Study Completion Date

June 30, 2025

Conditions
Relapsed/Refractory B-Cell Lymphoma
Interventions
DRUG

FT522

FT522 drug product is administered as an intravenous infusion on Days 1, 4 and 8 of a treatment cycle.

DRUG

Rituximab

Rituximab will be administered as an IV infusion on Day -4 of the treatment cycle.

DRUG

Cyclophosphamide

Cyclophosphamide will be administered as an IV infusion at a dose of 500 mg/m\^2 on Day -5, Day -4, and Day -3 of the treatment cycle.

DRUG

Fludarabine

Fludarabine will be administered as an IV infusion at a dose of 30 mg/m\^2 on Day -5, Day -4, and Day -3 of the treatment cycle.

DRUG

Bendamustine

Bendamustine will be administered as an IV infusion at a dose of 90 mg/m\^2 on Day -5 and Day -4 of the treatment cycle. Bendamustine may be administered as an alternative to cyclophosphamide/fludarabine.

Trial Locations (7)

32803

Advent Health, Orlando

37203

Tennessee Oncology, Nashville

48201

Karmanos Cancer Center, Detroit

55455

University of Minnesota Masonic Cancer Center, Minneapolis

68198

University of Nebraska Medical Center, Omaha

73104

OU Health Stephenson Cancer Center, Oklahoma City

77030

Baylor Houston Methodist Hospital, Houston

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Fate Therapeutics

INDUSTRY

NCT05950334 - FT522 With Rituximab in Relapsed/Refractory B-Cell Lymphoma (FT522-101) | Biotech Hunter | Biotech Hunter