Start Date
November 30, 2023
Primary Completion Date
March 31, 2025
Study Completion Date
September 30, 2025
Lorlatinib
Participants will receive assigned dose of daily oral lorlatinib continuously for each cycle. Each cycle is 3 weeks.
Cisplatin or Carboplatin
Participants will receive standard of care intravenous Cisplatin or Carboplatin, both chemotherapy medications, on day 1 of each cycle every 3 weeks, for Cycles 1-4. Each cycle is 3 weeks.
Pemetrexed
Participants will receive intravenous Pemetrexed, a chemotherapy medication, on day 1 of each cycle. Each cycle is 3 weeks.
Virginia Oncology Associates, Norfolk
Messino Cancer Center, Asheville
Tennessee Oncology, Nashville
Texas Oncology, Dallas
Sarah Cannon Research Institute at HealthONE, Denver
Collaborators (1)
Pfizer
INDUSTRY
SCRI Development Innovations, LLC
OTHER