Possible Diagnostic Protein Markers in Schistosoma Related Bladder Diseases.

Not yet recruitingOBSERVATIONAL
Enrollment

120

Participants

Timeline

Start Date

October 1, 2023

Primary Completion Date

June 30, 2025

Study Completion Date

October 30, 2027

Conditions
Schistosoma Haematobium
Interventions
DIAGNOSTIC_TEST

Immunohistochemistry staining,

"Tissue samples:~* Histopathological examination: Hematoxylin and Eosin slides will be prepared and examined.~ * The only dependable criterion for the diagnosis of bilharzial infestation is the microscopic detection of Bilharzia ova in pathological sections.~ * Pathology (cystitis- cancer and its grade staging will be reported in accordance with the 2022 World Health Organization Classification of Tumors of the Urinary System (17).~* To quantify levels of Nuclear factor kappa B and protein kinase c α:~ * Immunohistochemistry according to the manufacturer's instructions."

DIAGNOSTIC_TEST

microscopic examination of urine

"Urine samples:~* Mic roscopic examination (detection of S. haematobium egg - egg counting)~* Detection of HSP 70 Measurements: indirect ELISA will be used to quantify HSP concentrations in urine."

Trial Locations (1)

Assiut University71515

Assiut University Hospital, Asyut

All Listed Sponsors
lead

Assiut University

OTHER

NCT05941884 - Possible Diagnostic Protein Markers in Schistosoma Related Bladder Diseases. | Biotech Hunter | Biotech Hunter