21
Participants
Start Date
June 10, 2023
Primary Completion Date
May 10, 2025
Study Completion Date
June 1, 2026
neoadjuvant chemo-hypofractionated radiotherapy plus PD-1 antibody (Tislelizumab)
"1. Immunotherapy combined with chemotherapy (2 cycles): Intravenous tislelizumab (200mg, d1, q21d) in combination with XELOX regimen (capecitabine 1000 mg/m2 bid\*14d + oxaliplatin 130mg/m2, d1, q21d);~2. Concurrent radiotherapy: Within one week after the first initiation of chemo-immunotherapy, concurrent hypofractionated radiotherapy will be started: intensity modulated radiotherapy was given for tumors, total dose:30Gy/12f, 2.5Gy/f."
Jiangsu Cancer Hospital, Nanjing
Jiangsu Cancer Institute & Hospital
OTHER