A Single-arm, Open-label, Single-center Prospective Study of Fruquintinib Combined With Envafolimab in the Treatment of Advanced or Unresectable Locally Advanced Bone and Soft Tissue Sarcoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

April 1, 2023

Primary Completion Date

December 1, 2025

Study Completion Date

December 1, 2026

Conditions
Advanced or Unresectable Locally Advanced Bone and Soft Tissue Sarcoma
Interventions
DRUG

fruquintinib

VEGF receptor tyrosine-kinase inhibitor:fruquintinib(4mg), Oral,qd, d1-d14, Q3w,Until disease progression or intolerable toxicity occurs.

DRUG

Envafolimab

anti-PD-1 immune checkpoint inhibitor:Envafolimab(400mg), subcutaneous injection, d1, Q3w,Until disease progression or intolerable toxicity occurs.

Trial Locations (1)

Unknown

RECRUITING

Shanghai No.6 People Hospital, Shanghai

All Listed Sponsors
lead

Shanghai 6th People's Hospital

OTHER