Effects of Flumazenil on Recovery After Total Intravenous Anesthesia With Remimazolam

NARecruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

September 19, 2023

Primary Completion Date

February 28, 2026

Study Completion Date

June 30, 2026

Conditions
Flumazenil Adverse ReactionRemimazolamHip JointElderly Patients
Interventions
DRUG

Flumazenil

During induction, patients will receive remimazolam 6mg/kg/h with remifentanil TCI 1\~4 nanogram/mL. After patient loses consciousness, anesthesia will be maintained with remimazolam 1-2mg/kg/h combined with remifentanil. When procedure ends, infusion remimazolam stops and 0.3mg of flumazenil according to allocated groups.

DRUG

normal saline

During induction, patients will receive remimazolam 6mg/kg/h with remifentanil TCI 1\~4 nanogram/mL. After patient loses consciousness, anesthesia will be maintained with remimazolam 1-2mg/kg/h combined with remifentanil. When procedure ends, infusion remimazolam stops and 0.9% normal saline according to allocated groups.

Trial Locations (1)

50612

RECRUITING

Pusan National University Yangsan Hospital, Yangsan

All Listed Sponsors
lead

Pusan National University Yangsan Hospital

OTHER