Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH

PHASE2RecruitingINTERVENTIONAL
Enrollment

126

Participants

Timeline

Start Date

April 1, 2024

Primary Completion Date

June 1, 2027

Study Completion Date

December 1, 2027

Conditions
Chronic Obstructive Pulmonary DiseasePulmonary HypertensionDyspnea
Interventions
DRUG

Tadalafil

one or 2 encapsulated tablets of encapsulated tadalafil (20MG) po QD

DRUG

Placebo

one or two encapsulated tablets of placebo po QD

Trial Locations (5)

80045

RECRUITING

Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora

30033-4004

RECRUITING

Atlanta VA Medical and Rehab Center, Decatur, GA, Decatur

02130-4817

RECRUITING

VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston

68105-1850

RECRUITING

Omaha VA Nebraska-Western Iowa Health Care System, Omaha, NE, Omaha

02908-4734

RECRUITING

Providence VA Medical Center, Providence, RI, Providence

All Listed Sponsors
collaborator

VA Boston Healthcare System

FED

collaborator

Atlanta VA Medical Center

FED

collaborator

VA Eastern Colorado Health Care System

FED

collaborator

VA Nebraska Western Iowa Health Care System

FED

lead

VA Office of Research and Development

FED