Examining the Role of Female Endogenous Sex Hormones in Eccentric Exercise

NARecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

March 7, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

August 31, 2026

Conditions
Inflammatory Response
Interventions
BEHAVIORAL

Eccentric leg extension

Participants will complete a 10 x 10 eccentric leg extension on a Cybex Norm dynamometer. Upon arrival, participants will be asked their perceived readiness to perform on a 11 point numeric rating scale. Before the running protocol a baseline blood sample will be collected, as well as passive and active delayed onset muscle soreness (DOMS), a countermovement jump. Half way through each set (i.e., after the 5th repetition) participants will be asked to rank their level of difficulty on a 11 point OMNI Res scale. This will occur during each set. Participants will have follow up blood draws, measures of muscle function (i.e, jump height) and soreness measured immediately after and 24 and 48 hours post-exercise.

Trial Locations (1)

90033

RECRUITING

Clinical Exercise Research Center, Los Angeles

All Listed Sponsors
lead

University of Southern California

OTHER