4D-150 in Patients With Diabetic Macular Edema

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

August 9, 2023

Primary Completion Date

February 28, 2029

Study Completion Date

February 28, 2029

Conditions
Diabetic Macular EdemaDiabetic Retinopathy
Interventions
BIOLOGICAL

4D-150 IVT

4D-150: AAV-based gene therapy comprised of miRNA targeting VEGF-C and codon-optimized sequence encoding aflibercept.

BIOLOGICAL

Aflibercept IVT

Commercially available Active Comparator

Trial Locations (6)

16507

Erie Retina Research, Erie

21740

Cumberland Valley Retina Consultants, Hagerstown

24502

Piedmont Eye Center, Lynchburg

78750

Austin Clinical Research, Austin

97401

Verum Research, LLC, Eugene

X00612

Emanuelli Research and Development Center, Arecibo

Sponsors
All Listed Sponsors
lead

4D Molecular Therapeutics

INDUSTRY