12
Participants
Start Date
January 1, 2023
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2026
CAR-GPC3 T cells
Subjects will undergo leukapheresis to isolate peripheral blood mononuclear cells (PBMCs) for the production of JWATM214 . During JWATM214 production, subjects will receive a preconditioning chemotherapy regimen of cyclophosphamide and fludarabine to deplete the lymphocytes. After lymphodepletion, subjects will receive single-dose treatment with JWATM214 by intravenous (IV) injection.
RECRUITING
Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai
RenJi Hospital
OTHER