Isatuximab, Bela Maf, Pom, and Dex in Relapsed/Refractory Multiple Myeloma

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

June 18, 2024

Primary Completion Date

December 1, 2025

Study Completion Date

December 1, 2026

Conditions
Relapsed CancerRefractory Multiple MyelomaMultiple Myeloma
Interventions
DRUG

Isatuximab

An IgG1-derived monoclonal antibody that targets CD38 proteins, administered intravenously.

DRUG

Belantamab mafodotin

An antibody-drug conjugate that is the combination of an antibody targeting BCMA and a drug, administered intravenously.

DRUG

Pomalidomide

An immunomodulatory agent, capsule taken orally.

DRUG

Dexamethasone

A glucocorticoid which is a substance that stops inflammation cause by immune system disorders, tablet taken orally.

Trial Locations (2)

02114

Massachusetts General Hospital, Boston

02215

Dana-Farber Cancer Institute, Boston

Sponsors

Collaborators (2)

All Listed Sponsors
collaborator

Sanofi

INDUSTRY

collaborator

GlaxoSmithKline

INDUSTRY

lead

Massachusetts General Hospital

OTHER

NCT05922501 - Isatuximab, Bela Maf, Pom, and Dex in Relapsed/Refractory Multiple Myeloma | Biotech Hunter | Biotech Hunter