Clinical and Metabolic, Immunological and Microbiological Characteristics of Obese Patients

Active, not recruitingOBSERVATIONAL
Enrollment

50

Participants

Timeline

Start Date

April 2, 2023

Primary Completion Date

December 15, 2025

Study Completion Date

April 2, 2026

Conditions
Obesity
Interventions
DIAGNOSTIC_TEST

Determination of the level of interleukins in the blood, stool analysis for the intestinal microbiome, general clinical tests, glucose tolerance test, hormonal profile

"comprehensive laboratory and instrumental diagnostics in accordance with federal clinical guidelines on obesity (Peterkova V. A., 2021), including:~* general blood test, general urine test,~* biochemical blood analysis (total protein, urea, creatinine, total bilirubin, AST, ALT, total cholesterol, high and low density lipoproteins, triglycerides, uric acid, alkaline phosphatase, C-reactive protein),~* hormonal profile (T4 free, TSH, cortisol, C-peptide, fasting insulin, stimulated insulin),~* glycated hemoglobin,~* \- glucose tolerance test,~* ultrasound examination of abdominal organs, kidneys (in the presence of arterial hypertension),~* blood pressure monitoring.~Special laboratory methods:~* Blood test to determine the level of HCRP, pro-inflammatory cytokines (leptin, IL-1b, IL-6, IL-8, tumor necrosis factor-α).~* analysis of feces for microbiota by MALDI-TOF mass spectrometry,~* bioimpedance measurement."

Trial Locations (1)

443079

Samara State Medical University, Samara

All Listed Sponsors
lead

Samara State Medical University

OTHER