VTE Prevention With Rivaroxaban in Genitourinary Cancer Patients Receiving Systemic Therapy

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

November 4, 2024

Primary Completion Date

October 31, 2026

Study Completion Date

October 31, 2026

Conditions
Venous ThromboembolismUrologic Cancer
Interventions
DRUG

Rivaroxaban 10 MG

The intervention in the experimental arm will be rivaroxaban, 10 mg PO once daily (prophylactic dosing) for 180 days after the start of systemic therapy or until one of the primary study outcomes occurs (VTE or major bleeding).

OTHER

Placebo control

Identical to Rivaroxaban intervention except participants will receive a matched placebo instead of the study drug

Trial Locations (1)

K1H 8L6

RECRUITING

Ottawa Hospital Research Institute, Ottawa

All Listed Sponsors
collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

collaborator

Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR) Network

NETWORK

collaborator

Kidney Cancer Research Network of Canada

UNKNOWN

lead

Ottawa Hospital Research Institute

OTHER