Aqueous vs Alcohol Chlorhexidine Skin Preparation for Prevention of Cesarean Section Wound Infections

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

1,470

Participants

Timeline

Start Date

October 9, 2023

Primary Completion Date

October 31, 2025

Study Completion Date

October 31, 2025

Conditions
Surgical Site InfectionCesarean Section; Infection
Interventions
DRUG

2% Chlorhexidine gluconate with 70% alcohol

Patients will be prepared similarly using the appropriate number of 26mL Chloraprep sticks for their body surface area. The lever will be pinched to activate the ampoule and release the antiseptic. The solution will be given time to partially load in the sponge. The sponge will be pressed against the skin area where the incision is intended moving back and forth for 30 sec , then working up towards the upper edge of the surgical field and then working from below the incision sight to the upper thighs. The antiseptic will be given time to dry (3 min)

DRUG

4% Chlorhexidine Gluconate aqueous solution

Patients will be scrubbed preoperative with an applicator that contain 4% chlorohexidine aqueous solution (3 consecutive applications) liberally over 2 minutes followed by drying with sterile towel. The area scrubbed will be the same as the chloraprep group.

Trial Locations (1)

15260

University of Pittsburgh, Pittsburgh

All Listed Sponsors
lead

Yaneve Fonge

OTHER

NCT05920122 - Aqueous vs Alcohol Chlorhexidine Skin Preparation for Prevention of Cesarean Section Wound Infections | Biotech Hunter | Biotech Hunter