Effects of rTMS on Food Choice in Anorexia Nervosa

NAActive, not recruitingINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

April 24, 2023

Primary Completion Date

June 30, 2028

Study Completion Date

June 30, 2028

Conditions
Anorexia Nervosa
Interventions
DEVICE

High-frequency repetitive transcranial magnetic stimulation (active rTMS)

HF-rTMS is applied with a figure-of-8 coil using the Magstim TMS System. Participants receive one administration of HF-rTMS, delivered to the region of the right dorsolateral prefrontal cortex (DLPFC) with greatest resting-state functional connectivity to the dorsal striatum (individualized per participant). HF-rTMS is delivered at a frequency of 10 Hz for approximately 37 minutes (3000 total pulses).

DEVICE

Sham repetitive transcranial magnetic stimulation (sham rTMS)

Sham rTMS is applied with a figure-of-8 sham coil using the Magstim TMS System, which is identical to the active coil, replicates the sounds of HF-rTMS, and is designed to mimic sensations of HF-rTMS. Participants receive one administration of sham rTMS, delivered to the region of the right dorsolateral prefrontal cortex (DLPFC) with greatest resting-state functional connectivity to the dorsal striatum (individualized per participant). Sham rTMS is delivered for approximately 37 minutes (3000 total pulses).

Trial Locations (1)

10032

New York State Psychiatric Institute, New York

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

collaborator

National Eating Disorders Association

OTHER

collaborator

Global Foundation for Eating Disorders

UNKNOWN

lead

New York State Psychiatric Institute

OTHER