Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patients

NARecruitingINTERVENTIONAL
Enrollment

250

Participants

Timeline

Start Date

July 10, 2023

Primary Completion Date

July 1, 2026

Study Completion Date

December 1, 2026

Conditions
Obesity, MorbidExtubation Failure
Interventions
DEVICE

Noninvasive ventilation alternating with high flow nasal cannula

A total of 24 hours of prophylactic respiratory support will be provided using NIV alternating with HFNC with total NIV usage of 16 hours and HFNC usage of 8 hours.

DEVICE

High flow nasal cannula

A total of 24 hours of prophylactic respiratory support will be provided using HFNC alone.

Trial Locations (5)

44280

RECRUITING

Hospital Civil Fray Antonio Alcalde, Guadalajara

53226

RECRUITING

Medical College of Wisconsin, Milwaukee

60190

NOT_YET_RECRUITING

Central DuPage Hospital, Winfield

60612

RECRUITING

Rush University Medical Center, Chicago

77030

RECRUITING

McGovern Medical School, The University of Texas Health Science Center, Houston

All Listed Sponsors
collaborator

Hospital Civil de Guadalajara

OTHER

collaborator

Medical College of Wisconsin

OTHER

collaborator

The University of Texas Health Science Center, Houston

OTHER

collaborator

Central DuPage Hospital

OTHER

lead

Rush University Medical Center

OTHER