Combination of RC48 and Tislelizumab for Renal Preservation in High-risk UTUC Patients

PHASE2RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

June 10, 2023

Primary Completion Date

December 30, 2025

Study Completion Date

December 30, 2026

Conditions
Upper Urinary Tract Urothelial CarcinomaKidney PreservationHER-2 ADCPD-1antibody
Interventions
DRUG

RC48 Combined With Tislelizumab

"In this trial, RC48 was scheduled to be administered at a dose of 2.0 mg/kg every 3 weeks, with the first dose on day 1 of the first cycle.~Tislelizumab was administered at a dose of 200 mg every 3 weeks, with the first dose on day 1 of the first 21-day cycle. The drug is diluted with normal saline and administered by intravenous drip for one hour."

Trial Locations (1)

Unknown

RECRUITING

Ethics Committee of Shanghai Renji Hospital, Shanghai

All Listed Sponsors
collaborator

Tianjin Medical University Second Hospital

OTHER

collaborator

Peking University First Hospital

OTHER

collaborator

West China Hospital

OTHER

lead

RenJi Hospital

OTHER